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. Author manuscript; available in PMC: 2012 Jan 23.
Published in final edited form as: Org Lett. 2009 Dec 3;11(23):5370–5373. doi: 10.1021/ol901999f

Figure 1.

Figure 1

Proteomimetics of the NR box. a) The NR box forms an alpha helix and consists of an LXXLL residue pattern. b) Bis-4,4’-oxyphenyl scaffold (energetically minimized). Note the rotation of the biaryl core. c) Target compounds 1a–e with varying 3,3’ substitution.