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(a) Nordlinger prognostic system
| Risk | N | No. of risk factors | 2-year survival |
|---|---|---|---|
| Low | 305 | 0–2 | 79% |
| Intermed | 738 | 3-4 | 60% |
| High | 230 | 5–7 | 43% |
Risk factors are (1) age > 60 years, (2) extension of primary CRC into serosa, (3) node-positive primary CRC, (4) time interval from primary CRC to CRLM < 2 years, (5) size of largest CRLM ≥ 5 cm, (6) number of CRLM ≥ 4, (7) margin less than 1 cm [16].
