Table 2.
Blood glucose level (mmol/L) in alloxan-induced diabetic rats after oral administration of metformin, WSF of okra and CMC in alloxan-induced diabetic rats.
Treatment groups | 0 hr | 2 hrs | 4 hrs | 8 hrs | 12 hrs | 24 hrs |
---|---|---|---|---|---|---|
NC | 4.8 ± 0.04 | 4.6 ± 0.20 | 4.7 ± 0.19 | 4.78 ± 0.02 | 4.69 ± 0.15 | 4.9 ± 0.03 |
DC | 33.2 ± 1.02 | 32.85 ± 0.14 | 33.7 ± 1.01 | 34.6 ± 1.35 | 34.6 ± 0.06 | 34.2 ± 1.05 |
MC | 32.0 ± 0.40 | 15.2 ± 0.09 | 14.9 ± 1.0 | 17.3 ± 0.04 | 17.8 ± 1.90 | 20.2 ± 1.01 |
DMF | 33.5 ± 1.05 | 33.6 ± 0.95a | 32.2 ± 1.35a | 32.3 ± 2.04a | 32.8 ± 1.02a | 34.2 ± 1.07a |
DMC | 33.6 ± 0.19 | 32.2 ± 0.40a | 25.4 ± 0.1a | 30.0 ± 1.24a | 30.6 ± 0.14a | 33.2 ± 0.09a |
Values are expressed as mean ± SEM of 6 rats/group. NC: normal control; DC: diabetic control; MC: diabetic with metformin only (metformin control); DMF: diabetic with metformin and WSF of A. esculentus; DMC: diabetic with metformin and CMC. a P < 0.05 compared to MC (ANOVA followed by Dunnett's test).