Table 3. Feasibility of analyzing between-center variation.
VSD | TOF | AVC | ASO | ASO+VSD | Fontan | Truncu s |
Norwood | |
---|---|---|---|---|---|---|---|---|
Number of participants included in analysis | 74 | 74 | 73 | 70 | 65 | 71 | 66 | 69 |
Aggregate mortality rate | 0.64% | 1.1% | 2.2% | 2.9% | 7.0% | 1.3% | 10.9% | 19.3% |
Sample size required for 50% power to detect 2x increase in mortality | 599 | 338 | 172 | 131 | 48 | 304 | 31 | 17 |
Number of participants meeting mortality requirement | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 40 |
Number of participants meeting PLOS requirement (≥5 cases) | 73 | 72 | 65 | 60 | 44 | 64 | 33 | 59 |