Figure 2.
Fluorescent images in pseudo-colour of a typical intercellular calcium signal propagation process in a linear bone cell chain. The cell at the right end has been mechanically stimulated by an atomic force microscope probe from 60 s. Its [Ca2+]i intensity reached the peak 6 s later. The calcium signalling was later transferred to the other cells on its left side, and all three cells released calcium spikes sequentially. The white arrowheads highlight the cell with peak [Ca2+]i at the image-taken time, which is shown on the right.