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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Future Oncol. 2011 Dec;7(12):1457–1473. doi: 10.2217/fon.11.121

Figure 6. Adipose-derived stem cells form podoplanin-positive tubular structures following VEGF-C stimulation or TGF-β1 inhibition.

Figure 6

(A) Counts of podoplanin-positive vessels/HPF in Matrigel plugs harvested from various groups (left; mean + standard deviation) and (B) representative image of podoplanin-positive vessels (arrows). Note significant increase in number of podoplanin-positive vessels/HPF in groups treated with ASCs transfected with DN-RII virus or stimulated with VEGF-C prior to implantation (***p < 0.001). Also note the additive effect of DN-RII transfection (**p < 0.01). Scale bar represents 50 μm. ASC: Adipose-derived stem cell; B-Gal: B-galactosidase; DN-RII: Dominant-negative TGF-β receptor II; HPF: High-powered field.