Table 1.
Compound | E. coli | S. aureus |
M. tuberculosis |
|
---|---|---|---|---|
Wild type | ClpP1 overexpressor | |||
IDR-10001 | >100 | 1 | 100 | 100 |
ADEP2 | NT | 1.25 | 25 | 25 |
ADEP3 | NT | >100 | 100 | 100 |
ADEP4 | NT | 0.125 | 50 | 50 |
IDR-10011 | >100 | 5 | 50 | 50 |
MIC99 (μg/ml) was determined against each bacterial species on solid medium.
NT, not tested.