Fig 2.

SecA hybrid proteins. (A) Overall domain structure of SecA. The functional SecA domains and subdomains are indicated as defined previously (15, 25). NBD, nucleotide binding domain; PBD, preprotein binding domain; IRA2, intramolecular regulator of ATPase 2; SD, scaffold domain, WD, wing domain; IRA1, intramolecular regulator of ATPase 1; CTL, C-terminal linker; CTD, C-terminal domain. (B) Schematic representation of SecA hybrid proteins used in this study. The numbers in parentheses correspond to the amino acids that are derived from the indicated parental SecA proteins. The respective fusion sites are indicated by an arrow.