Table 1.
Sensitivity and specificity for QVL assay results among HIV-exposed infants and cases of suspected acute HIV infection who had multiple detectable QVL and/or follow-up serological tests to confirm their statusa
| Population | No. positive by QVL assay/no. positive by serial serology and/or repeat detectable QVL | Sensitivity (%) (95% CI) | No. negative by QVL/no. negative by serial serology | Specificity (%) (95% CI) |
|---|---|---|---|---|
| HIV-exposed infants (n = 186) | 8/8 | 100 (63.1–100) | 178/178 | 100 (97.9–100) |
| Suspected acute HIV infection cases (n = 175) | 82/84b | 97.6 (91.6–99.7) | 91/91 | 100 (96.1–100) |
a
CI, confidence interval.
b
One of the two patients with serologically confirmed HIV infection had an initially undetectable QVL but a low viral load on a follow-up QVL (see text).