Table 7.
Associations of the MIGs with one another and with the selected known virulence genes in the 231 UTI-associated E. coli isolatesa
| Gene |
P value |
|||||
|---|---|---|---|---|---|---|
| cjrABC-senB | eco274 | sivH | fbpB | sisA | sisB | |
| Identified | ||||||
| cjrABC-senB | NA | ++ | (++) | − | + | − |
| eco274 | ++ | NA | (++) | − | − | − |
| sivH | (++) | (++) | NA | ++ | ++ | − |
| fbpB | − | − | ++ | NA | + | + |
| sisA | + | − | ++ | + | NA | − |
| sisB | − | − | − | + | − | NA |
| Known | ||||||
| papG I | − | − | − | − | − | − |
| papG II | − | − | − | − | ++ | − |
| papG III | − | − | − | + | − | − |
| chuA | ++ | − | ++ | ++ | ++ | − |
| ompT | ++ | ++ | − | ++ | − | + |
| afa/draBC | − | − | − | − | − | − |
| sat | ++ | ++ | (++) | − | ++ | ++ |
| iha | ++ | ++ | (++) | − | ++ | ++ |
| cnf1 | − | (++) | ++ | ++ | − | ++ |
| usp | − | (++) | ++ | ++ | ++ | − |
| ireA | (++) | (++) | ++ | − | ++ | − |
| iroN | (++) | (++) | ++ | ++ | − | − |
| sfaS | − | (+) | ++ | ++ | − | − |
| ibeA | − | − | + | + | (+) | − |
| hlyA | − | − | + | ++ | − | ++ |
a
−, P ≥ 0.01; +, P < 0.01; ++, P < 0.001. Because of multiple comparisons, a P value of <0.01 was arbitrarily set as the threshold for statistical significance, with a P value of <0.05 as borderline statistical significance (12, 14). Parentheses indicate negative associations. “Identified” and “Known” indicate the MIGs and selected known virulence genes in this study, respectively.