Table 2.
Detection of respiratory pathogens by FilmArray RP and real-time PCR assays
| Organism | No. detected: FilmArray RP/PCR |
Positive % agreement |
Negative % agreement |
|||||
|---|---|---|---|---|---|---|---|---|
| +/+ (a) | +/− (b) | −/+ (c) | −/− (d) | a/(a + c) (%) | 95% CI | d/(b + d) (%) | 95% CI | |
| Adenovirus | 11 | 0 | 13 | 191 | 11/24 (45.8) | 27.9–64.9 | 191/191 (100) | 98.0–100 |
| Respiratory syncytial virus A | 16 | 0 | 1 | 198 | 16/17 (94.1) | 73.0–99.0 | 198/198 (100) | 98.1–100 |
| Respiratory syncytial virus B | 18 | 0 | 1 | 196 | 18/19 (94.7) | 75.4–99.1 | 196/196 (100) | 98.1–100 |
| Influenza A virus H1 | 17 | 0 | 0 | 198 | 17/17 (100) | 81.6–100 | 198/198 (100) | 98.1–100 |
| Influenza A virus H3 | 15 | 0 | 2 | 198 | 15/17 (88.2) | 65.7–96.7 | 198/198 (100) | 98.1–100 |
| Influenza A virus 2009 H1 | 16 | 0 | 1 | 198 | 16/17 (94.1) | 73.0–99.0 | 198/198 (100) | 98.1–100 |
| Influenza B virus | 15 | 0 | 2 | 198 | 15/17 (88.2) | 65.7–96.7 | 198/198 (100) | 98.1–100 |
| Parainfluenza virus type 1 | 16 | 0 | 1 | 198 | 16/17 (94.1) | 73.0–99.0 | 198/198 (100) | 98.1–100 |
| Parainfluenza virus type 2 | 15 | 0 | 2 | 198 | 15/17 (88.2) | 65.7–96.7 | 198/198 (100) | 98.1–100 |
| Parainfluenza virus type 3 | 16 | 0 | 1 | 198 | 16/17 (94.1) | 73.0–99.0 | 198/198 (100) | 98.1–100 |
| Metapneumovirus | 16 | 0 | 4 | 195 | 16/20 (80) | 58.4–91.9 | 195/195 (100) | 98.1–100 |
| Rhinovirus | 30 | 7 | 0 | 178 | 30/30 (100) | 88.7–100 | 178/185 (96.2) | 92.4–98.6 |
| Bocavirus | 17 | 3 | 0 | 3 | 17/17 (100) | 81.6–100 | 3/6 (50) | 18.8–81.2 |
| B. pertussis | 9 | 0 | 0 | 12 | 9/9 (100) | 70.1–100 | 12/12 (100) | 75.8–100 |
| M. pneumoniae | 9 | 0 | 0 | 13 | 9/9 (100) | 70.1–100 | 13/13 (100) | 77.2–100 |
| Total | 236 | 10 | 28 | 2,372 | 236/264 (89.4) | 85.1–92.6 | 2,372/2,382 (99.6) | 99.2–99.8 |