Table 1.
Correlation of multiplex xTAG fungal ASR assay results with fungal culture results
| Organism(s) detected | No. of positive blood culture samples (n = 122) |
No. of positive xTAG assay samplesa | Avg MFI ± SD | |
|---|---|---|---|---|
| From patients | Spiked | |||
| C. albicans | 28 | 1 | 29 | 12,056 ± 2,112 |
| C. glabratab | 19 | 1 | 20 | 7,373 ± 1,667 |
| C. parapsilosisb | 9 | 2 | 11 | 7,428 ± 364 |
| C. neoformans | 3 | 2 | 5 | 8,069 ± 2,681 |
| C. krusei | 3 | 2 | 5 | 9,308 ± 1,703 |
| C. tropicalis | 4 | 1 | 5 | 8,063 ± 3,205 |
| C. guilliermondii | 1 | 3 | 4 | 9,930 ± 1,923 |
| C. lusitaniae | 0 | 2 | 2 | 10,815 ± 344 |
| C. parapsilosis, C. neoformans | 2 | 0 | 2 | 7,684 ± 153, 8,343 ± 1,662 |
| C. albicans, C. glabrata | 1 | 0 | 1 | |
| C. glabrata, C. parapsilosis | 1 | 0 | 1 | |
| C. krusei, C. guilliermondii | 0 | 1 | 1 | |
| C. krusei, C. parapsilosis | 0 | 1 | 1 | |
| C. glabrata, C. dubliniensis | 1 | 0 | 1 (C. glabrata) | |
| C. dubliniensis | 3 | 0 | ND | 0 |
| Aureobasidium pullulans | 1 | 0 | ND | 0 |
| Candida norvegensis | 0 | 1 | ND | 0 |
| Rhodotorula spp. | 1 | 0 | ND | 0 |
| Saccharomyces cerevisiae | 2 | 0 | ND | 0 |
| C. ciferrii | 0 | 1 | 1 (C. neoformans) | |
| Staphylococcus aureus | 6 | 0 | ND | 0 |
| Coagulase-negative staphylococci | 5 | 0 | ND | 0 |
| Escherichia coli | 2 | 0 | ND | 0 |
| Enterococcus faecalis | 2 | 0 | ND | 0 |
| Streptococcus pneumoniae | 2 | 0 | ND | 0 |
| Klebsiella oxytoca | 1 | 0 | ND | 0 |
| Klebsiella pneumoniae | 1 | 0 | ND | 0 |
| Abiotrophia spp. | 1 | 0 | ND | 0 |
| B. fragilis | 1 | 0 | ND | 0 |
| Viridans group streptococci | 1 | 0 | ND | 0 |
| Chryseomonas spp. | 1 | 0 | ND | 0 |
| E. coli, S. aureus | 1 | 0 | ND | 0 |
| Enterobacter spp., Streptococcus spp. | 1 | 0 | ND | 0 |
| Total | 104 | 18 | ||
a
ND, not determined.
b
One culture was coinfected with coagulase-negative staphylococci.