Table 3.
Patient categorya | No. (%) of BAL fluid samples | No. of patients (%) | IFA-positive/qPCR-positive samples |
IFA-negative/qPCR-positive samples |
IFA-negative/qPCR-negative samples |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total (%) | Mean log copy no. (SD) | No. from patients with: |
Total (%) | Mean log copy no. (SD) | No. from patients with: |
Total (%) | No. from patients with: |
||||||
Lesionsb | PcP prophylaxis | Lesionsb | PcP prophylaxis | Lesionsb | PcP prophylaxis | ||||||||
Total | 353 | 287 | 17 | 15 | 1 | 63 | 27 | 2 | 273 | 94 | 51 | ||
HIV+ patients | 46 (13) | 39 (14) | 8 (47) | 5.5 (0.9) | 8 (53) | 0 | 4 (6) | 2.1 (1.2) | 3 (11) | 0 | 34 (12) | 15 (16) | 19 (37) |
≥200 CD4+ T cells/μl | 16/46 | 13/39 | 0/8 | 0 | 1/4 | 0 | 0 | 15/34 | 8/15 | 4/19 | |||
<200 CD4+ T cells/μl | 30/46 | 26/39 | 8/8 | 8/8 | 0 | 3/4 | 3/3 | 0 | 19/34 | 7/15 | 15/19 | ||
Hematology patients | 147 (42) | 111 (39) | 6 (35) | 4.2 (0.8) | 4 (27) | 0 | 24 (38) | 1.3 (0.9) | 8 (30) | 2 (100) | 117 (43) | 36 (38) | 22 (43) |
Acute leukemia | 73/147 | 49/111 | 3/6 | 3/4 | 0 | 15/24 | 4/8 | 0 | 55/117 | 18/36 | 9/22 | ||
CLD | 74/147 | 62/111 | 3/6 | 1/4 | 0 | 9/24 | 4/8 | 2/2 | 62/117 | 18/36 | 13/22 | ||
SOT recipients | 57 (16) | 47 (16) | 2 (12) | 4.6 (0.7) | 2 (13) | 1 | 10 (15.9) | 1.4 (1.0) | 3 (11) | 0 | 45 (16) | 17 (18) | 6 (12) |
Heart | 11/57 | 11/47 | 0/2 | 0 | 0 | 4/10 | 0 | 0 | 7/45 | 2/17 | 2/6 | ||
Liver | 17/57 | 13/47 | 2/2 | 2 | 1 | 1/10 | 1/3 | 0 | 14/45 | 5/17 | 2/6 | ||
Kidney | 29/57 | 23/47 | 0/2 | 0 | 0 | 5/10 | 2/3 | 0 | 24/45 | 10/17 | 2/6 | ||
Patients with SID | 53 (15) | 47 (16) | 1 (6) | 3.5 | 1 (7) | 0 | 16 (25.4) | 0.7 (1.0) | 6 (22) | 0 | 36 | 10 (11) | 3 (6) |
Patients with solid tumors | 18 (5) | 16 (6) | 0 | 0 | 0 | 0 | 7 (11.1) | 1.3 (1.4) | 6 (22) | 0 | 11 | 4 (4) | 1 (2) |
Others | 32 (9) | 27 (9) | 0 | 0 | 0 | 0 | 2 (3) | 0.2 (0.1) | 1 (4) | 0 | 30 | 12 (13) | 0 |
CLD, chronic lymphoproliferative disorders; SOT, solid-organ transplant; SID, systemic inflammatory diseases.
Diffuse radiological lesions.