Fig 1.
Estimated relationships between the probabilities of clinical (A) or microbiological (B) success and tigecycline fAUC0–24:MIC ratio, based on univariable logistic regression models (P = 0.023 and 0.031, respectively). The solid lines represent the estimated logistic regression functions, while the dashed-dotted lines represent the upper and lower 95% pointwise confidence bounds. The histogram represents the distribution of observed fAUC0–24:MIC ratio values. The solid boxes on the estimated logistic regression functions represent the thresholds for fAUC0–24:MIC ratios of 0.9 and 0.35 for the probabilities of clinical and microbiological success, respectively, which were derived based on classification trees.