Table 1.
Case no. | Hospital | Ward/dayb | Age (yr)/sex | APACHE II score | Underlying diseases | Invasive devices | Source/infectionc | Concomitant isolated | Treatment/appropriate antimicrobial therapye | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
1 | TVGH | NSCU/11 | 77/M | 22 | Traumatic ICH, SDH, SAH | Tracheostomy, CVC, Foley, ventilator | Blood/I | Pseudomonas aeruginosa | Ticarcillin/clavulanate for 18 days/no | Survived |
2 | TVGH | RCU/25 | 75/F | 21 | COPD, DM, hypertension, recent CVA | Tracheostomy, CVC, Foley, ventilator | Blood/I | None | Cefmetazole for 2 days, piperacillin-tazobactam for 3 days, and imipenem for 13 days/no | Survived |
3 | TVGH | ICUB/7 | 21/M | 19 | Pulmonary contusion with pulmonary hemorrhage and hemothorax | Swan-Ganz catheter, CVC, chest tube, ventilator | Blood/I | None | Ciprofloxacin for 14 days/yes | Survived |
4 | TVGH | CCU/14 | 87/M | 18 | Recent myocardial infarction | None | Blood/I | None | Flomoxef plus netilmycin for 9 days/no | Survived |
5 | TVGH | ICUA/7 | 24/F | 13 | Systemic lupus erythematosus | Arterial line, CVC, Foley, ventilator | Sputum/C | Pneumocystis jirovecii | —/—f | Died of other causes |
6 | TVGH | ICUA/13 | 81/F | 28 | Parkinson's disease, DM, hypertension | Arterial line, CVC, Foley, ventilator | Sputum/I | Stenotrophomonas maltophilia | Piperacillin-tazobactam for 21 days/no | Died of other causes |
7 | TVGH | ICUC/5 | 69/M | 39 | Multiple myeloma, old CVA | Arterial line, CVC, Foley, ventilator | Sputum/I | None | Imipenem for 14 days/no | Died of infection |
8 | NTUH | NA | NA | NA | NA | NA | Blood/I | NA | NA | NA |
9 | TVGH | CCU/26 | 80/F | 33 | Congestive heart failure, asthma, DM, hypertension | Arterial line, CVC, Foley, ventilator, HD via FVC | Blood/I | None | Levofloxacin for 10 days/yes | Died of other causes |
10 | TVGH | ER | 62/M | 11 | Lung cancer, chemotherapy | None | Blood/I | Chryseobacterium meningosepticum | Cefoperazone plus sulbactam for 5 days/no | Survived |
Abbreviations: TVGH, Taipei Veterans General Hospital; NTUH, National Taiwan University Hospital; NSCU, neurosurgical care unit; RCU, respiratory care unit; ICU, intensive care unit; CCU, cardiac care unit; NA, data not available; ER, emergency room; ICH, intracerebral hemorrhage; SDH, subdural hemorrhage; SAH, subarachnoid hemorrhage; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; CVA, cerebrovascular accident; CVC, central venous catheter; HD, hemodialysis; FVC, femoral vein catheter; Foley, Foley catheter; I, infection; C, colonization.
Ward at which the patient resided and days of admission when the first isolate of non-A. baumannii species harboring blaOXA-51-like genes was collected.
Infection (I) or colonization (C).
Organisms isolated or identified from the same site and at the same time with non-A. baumannii species.
Appropriate antimicrobial therapy was defined as therapy with at least one antimicrobial agents that had in vitro activity against the causative pathogen and administrated within 48 h after the acquisition of index clinical sample for culture.
—/—, since the patient was colonized with non-A. baumannii species, antimicrobial therapy for acinetobacters was not warranted.