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. 2012 Feb;56(2):613–617. doi: 10.1128/AAC.05606-11

Table 2.

Efficacies of daptomycin and vancomycin in a murine model of foreign-body infection caused by strains SE284 and SE385

Strain Treatment No. of xxx Bacterial concn (mean ± SD)
Sterile blood cultures (%) Survival (%)
Liver (log10 CFU/g) Catheter (log10 CFU/ml)
SE284 Control 15 9.39 ± 0.52 6.56 ± 0.65 0 0
Daptomycin 14 1.69 ± 2.28a 0.69 ± 1.22a,b 86.7a 66.7a
Vancomycin 14 4.20 ± 3.12a 3.69 ± 2.70a 57.1a 42.9a
SE385 Control 14 9.93 ± 0.88 5.98 ± 0.90 0 0
Daptomycin 15 1.66 ± 2.81a,b 0.42 ± 1.26a 100a 93.3a
Vancomycin 14 4.56 ± 2.61a 1.20 ± 1.92a 76.9a 76.9a
a

P < 0.05 compared with the internal control group.

b

P < 0.05 compared with the vancomycin group.