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. 2012 Feb;56(2):623–633. doi: 10.1128/AAC.05549-11

Table 1.

Relative fitness values of viruses containing a PI resistance-associated mutation compared to wild type determined using a growth competition assay

Virus Relative fitness value (mean ± SD)
M46I/WT 1.00 ± 0.03
G48V/WT 0.53 ± NDa
L63P/WT 1.02 ± 0.12
V82A/WT 0.85 ± 0.06
I84V/WT 0.78 ± 0.04
L90M/WT 0.98 ± 0.04
a

ND, not determined.