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Antiviral potencies of HNG-156 against replication-competent viruses
| Subtype/tropism | Virus name | EC50 (μM)a |
|---|---|---|
| A/R5 | A1 | 0.35 ± 0.11 |
| B/R5 | BaL | 0.005 ± 0.0004 |
| C/R5 | C5 | 0.65 ± 0.09 |
| D/R5 | D107 | 0.17 ± 0.07 |
Determined based on the infection of TZM-bl target cells with replication-competent HIV-1. See Table 1, footnote a, for data treatment. Experimental deviation was calculated as the standard error of the mean. All assays were repeated a minimum of three independent times in triplicate wells.
