Table 2.
Response to inoculation with live H. ducreyi
| Volunteera (gender) | Observation period (days) | Strainb | Dose (CFU)c | No. of initial papules | Final outcome of papule |
|
|---|---|---|---|---|---|---|
| No. resolved | No. of pustules | |||||
| 395 (F) | 7 | P | 32 | 3 | 1 | 2 |
| M | 24–97 | 3 | 3 | |||
| 396 (F) | 13 | P | 32 | 1 | 1 | |
| M | 24–97 | 2 | 2 | |||
| 397 (F) | 8 | P | 32 | 3 | 3 | |
| M | 24–97 | 3 | 1 | 2 | ||
| 398 (M) | 6 | P | 63 | 3 | 3 | |
| M | 23–91 | 2 | 1 | 1 | ||
| 400 (F) | 7 | P | 63 | 3 | 1 | 2 |
| M | 23–91 | 3 | 3 | |||
a
Volunteers 395, 396, and 397 were inoculated in the first group; volunteers 398 and 400 were inoculated in the second group. F, female; M, male.
b
P, parent strain 35000HP; M, mutant strain 35000HP-RSM208.
c
Doses are indicated as follows: 24–97, one dose each of 24, 48, and 97 CFU; 23–91, one dose each of 23, 46, and 91 CFU.