Fig 5.

Deletion of the two adrenergic kinases QseC and QseE impairs epinephrine-dependent regulation of multiple EHEC virulence factors. Shown are heat maps from microarray analysis representing the effects of epinephrine (Epi) on the wt and ΔqseC, ΔqseE, and ΔqseC ΔqseE mutant strains. The strains treated with epinephrine were compared to the same strains with no treatment. Red indicates upregulation, green indicates downregulation, and black indicates no change. (A) Heat map representing differential regulation of the LEE genes. (B) Heat map showing the differential expression of non-LEE genes.