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. 2012 Feb;86(3):1563–1576. doi: 10.1128/JVI.06480-11

Fig 8.

Fig 8

Effect of MAbs to the C-term of gD on virus neutralization by MC2. In each experiment, serial 2-fold dilutions of MC2 were mixed either with antibody IgGs or with a control lacking Ig (“no IgG”) and then incubated with 100 PFU of virus for 1 h at 37°C. The virus-antibody mixtures were added to Vero cells, and plaques were allowed to develop. (A) Neutralization by MC4 or MC2 or a combination of MC4 (33.3 nM) plus MC2. (B) Neutralization by MC10 or MC2 or a combination of MC10 (33.3 nM) plus MC2. (C) Neutralization by BD66 or MC2 or a combination of BD66 (80 nM) plus MC2. (D) Neutralization by DL6 or MC2 or a combination of DL6 (80 nM) plus MC2. The results are expressed as percentages compared to the no-Ig control. Results of a representative experiment are shown; each antibody was tested a minimum of three times.