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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Cell Physiol. 2012 Feb;227(2):416–420. doi: 10.1002/jcp.23031

Table 2. Clinical trials in the gene therapy of osteoarthritis.

Transgene Vector
Ex/In Vivo		 Phase PI,
Institution
or Sponsor		 OBA
Protocol
Number		 Status Number of
subjects
TGF-β1 Retrovirus
Ex Vivo		 I Ha,
Kolon Life
Sciences,
Korea		 NA Closed 12
TGF-β1 Retrovirus
Ex Vivo		 I Mont
TissueGene
Inc		 0307-594 Closed 9
TGF-β1 Retrovirus
Ex Vivo		 IIa Ha,
Kolon Life
Sciences,
Korea		 NA Recruitment
Complete		 28
TGF-β1 Retrovirus
Ex Vivo		 II Mont
TissueGene
Inc		 0912-1016 Open 100

OBA : Office of Biotechnology Activities

N = number of subjects in study

NA = Not Applicable