Table 8.
Characteristics and outcome of feline patients treated with pump inhibitors and chemotherapy
PATIENT | AGE | TUMOR |
PREV. TREATMENT |
THERAPY | OUTCOME (MONTHS) |
---|---|---|---|---|---|
DSH | 10 | BREAST CARCINOMA |
SURGERY MITOXANTRONE PD |
MITOXANTRONE | PR 4 |
DSH | 12 | ORAL SCC | MITOXANTRONE PD |
MITOXANTRONE | SD 2 |
DSH | 10 | ORAL SCC | SURGERY MITOXANTRONE PD |
MITOXANTRONE | CR 5+ |
DSH | 12 | ORAL SCC | BIOPSY MITOXANTRONE PD |
MITOXANTRONE | SD 6 |
DSH | 12 | LSA | MOPP × 3 months |
MOPP | CR 6+ |
DSH | 8 | NASAL LSA | MOPP PD |
MOPP | PR 3+ |
DSH | 7 | FSA | SURGERY, ECT × 2, CARBOPLATIN × 2 MITOXANTRONE × 2 |
MITOXANTRONE | PD |
Abbreviations: DSH: domestic short hair; ECT: electrochemotherapy; FSA: fibrosarcoma; LSA: lymphosarcoma; MOPP: mechlorethamine, oncovin (vincristine), prednisone, procarbazine; SCC: squamous cell carcinoma. +: still alive.
Drugs schedule: doxorubicin 30 mg/m2 every 21 days (pending hematological, cardiac and renal evaluation) up to 6 doses, carboplatin 210 mg/m2 every 21 days, mitoxantrone 6 mg/m2 every 21 days. For MOPP protocol see table 4 and 5.