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. 2012 Jan 23;7(1):e30612. doi: 10.1371/journal.pone.0030612

Figure 7. NLRP12 deficiency did not influence mucus production or collagen deposition in the lungs following HDM.

Figure 7

A) Mucus production was assessed following treatment with the Alcian blue/periodic acid-Schiffs reaction (AB/PAS) (20× original magnification). B) The volume of AB/PAS-stained mucosubstance per square millimeter of basal lamina (Vs) was determined. A significant increase in mucus was observed in the DMA mice; however, no significant differences were observed between the Nlrp12−/− and wild type mice. C) Masson's trichrome staining was used to assess collagen deposition in the lungs. Histopathology assessments revealed an increase in collagen deposition in the DMA treated animals compared to the saline treated mice. No significant differences were observed between the Nlrp12−/− and wild type mice. Saline, n = 6; Nlrp12−/−, n = 8; wild type, n = 12.