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. Author manuscript; available in PMC: 2012 Jan 23.
Published in final edited form as: Pregnancy Hypertens. 2011 Jan 1;1(1):87–94. doi: 10.1016/j.preghy.2010.10.002

Figure 3.

Figure 3

(A) Data are shown for mean ± SEM of viable fetuses in BALB/c+/+ (open bars) and Rag2 −/−/Il2rg−/− (solid bars) mice mated and euthanized within our colony. Either 3 or 4 litters were studied per histogram bar. Many more litters would need to be sacrificed to obtain an accurate estimation of fetal success for these genotypes. These preliminary data show however that viability of Rag2 −/−/Il2rg−/− is not disadvantaged compared with +/+. (B) Data are shown for mean± SEM cross sectional areas of placentae. Errors are too small for visualization of the error bars. A total of 135 tissues sections were scanned for each mean. At gd10, 12 and 14, there were no significant differences in placenta size between the genotypes. At gd 16, +/+ placentae were significantly larger (6.16mm2 ± 0.17 versus 5.4 mm2 ± 0.14 P<0.001) and there was no subsequent placental growth (+/+ placental size at gd18 was 5.99 mm2 ± 0.29). Rag2 −/−/Il2rg−/− placentae continued to grow and had a peripartum gd18 mean size of 7.02 mm2 ± 0.26. This was statistically larger (P<0.01) than in the +/+ females31.