Table 1.
Clinical, pathologic, and Molecular Findings in Epithelioid Hemangioendothelioma.
EHE Case # | Age | Sex | Location | Malig Grade | FISH rearrangements for WWTR1 & CAMTA1 | Clinical Follow-Up (mo) |
---|---|---|---|---|---|---|
1 | 68 | M | ST, arm | yes | +* | NED (16) |
2 | 59 | F | ST, groin | no | + | NED (116) |
3 | 39 | M | ST, subclavicle | yes | + | NED (14) |
4 | 54 | M | ST, arm | yes | +* | NED (108) |
5 | 52 | F | ST, abd wall, bilateral breast | yes | + | AWD (15) |
6 | 66 | M | ST, neck/shoulder | no | +* | NED (4) |
7 | 39 | F | ST, axilla | no | + | DOD (43) |
8 | 42 | F | IT, mediastinum, lung, SVC | yes | + | NED (23) |
9 | 34 | M | IT, lung, pleura | yes | + | DOD (4) |
10 | 32 | M | IT, pleura | yes | + | AWD (7) |
11 | 29 | F | IT, lung, paratracheal LNs | yes | + | LFU |
12 | 61 | M | IT, lung | no | + | DOD (82) |
13 | 65 | F | IT, lung | no | + | NED (20) |
14 | 55 | M | IT, lung | no | + | NED (30) |
15 | 41 | F | Liver | no | + | NED (7) |
16 | 48 | F | Liver | no | + | LFU |
17 | 25 | M | Bone/mandible | yes | + | DOD (24) |
EHE, epithelioid hemangioendothelioma, ST, soft tissue, IT, intra-thoracic, Malig, malignant,
RT-PCR confirmation of WWTR1-CAMTA1 fusion product, mo, months, NED, no evidence of disease, AWD, alive with disease, DOD, died of disease, LFU, lost follow-up.