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. Author manuscript; available in PMC: 2013 Jan 20.
Published in final edited form as: Cell. 2012 Jan 5;148(1-2):285–295. doi: 10.1016/j.cell.2011.12.007

Table 1.

Summary of in vivo chimera studies with rhesus monkey ESCs and embryos

Tested cells Host embryo stage Total offspring generated Developed to separate embryo Developed to embryo proper chimera
ORMES-22 Blastocyst 4 No No
ORMES-23 Blastocyst 2 No No
CRES-2 GFP Blastocyst 1 No No
Whole ICM Blastocyst 3 Yes Restricteda (hematopoietic)
4-cell embryo 4-cell embryo 10 No Yes
ORMES-22 GFP 4-cell embryo 1 No No
a

Chimerism was restricted to livers, spleens and placentas.

ORMES-22 (XX) and -23 (XY) are IVF-derived rhesus monkey embryonic stem cell lines. CRES-2 (XY) is SCNT-derived ESC line(Byrne et al., 2007)

(See also Tables S1 through S6, Figures S1 through S6, and Movie S1)