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. Author manuscript; available in PMC: 2013 Jan 17.
Published in final edited form as: Biochemistry. 2012 Jan 6;51(2):665–676. doi: 10.1021/bi201639x

Figure 5.

Figure 5

Thermal unfolding profiles of the Pitx2 homeodomain. Unfolded fractions of Pitx2 homeodomain wild-type and R24H plotted as a function of temperature. DNA free: wild-type (■), R24H (●). TAATCC bound: wild-type (▼), R24H (▲). Apparent Tm values for the wild-type free 42.0°C, R24H free 37/8°C, wild-type/TAATCC 58.5°C, R24H/TAATCC 54.2°C.