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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Brain Stimul. 2011 Feb 22;5(1):1–10. doi: 10.1016/j.brs.2011.01.009

Figure 1.

Figure 1

Schematic of experimental protocol for the temporary middle cerebral artery occlusion (TMCAO) studies which involved filament occlusion along with right common carotid occlusion (rCCAO) (A) and the permanent middle cerebral artery occlusion (PMCAO) studies produced by photothrombosis along with rCCAO (B). Changes in regional cerebral blood flow (CBF) were monitored with laser speckle contrast imaging. Over the first 30 minutes following MCA occlusion, the vagal nerve was not stimulated, with vagal nerve stimulation (VNS) starting 30 minutes into ischemia and lasting for 60 minutes.