Table 3.
Target | 2D similarity
|
|||
---|---|---|---|---|
FieldScreen | FLAP∷LBX | FLAP∷RBLB | MedusaScore + Filter | |
ace | 0.75 | 0.76 | 0.59 | 0.74 |
ache | 0.75 | 0.81 | 0.52 | 0.48 |
cdk2 | 0.72 | 0.50 | 0.49 | 0.70 |
cox2 | 0.88 | 0.88 | 0.68 | NA |
egfr | 0.58 | 0.50 | 0.45 | 0.64 |
fxa | 0.49 | 0.95 | 0.45 | 0.45 |
hivrt | 0.78 | 0.79 | 0.60 | 0.59 |
inha | 0.82 | 0.82 | 0.69 | 0.81 |
p38 | 0.66 | NA | 0.45 | 0.57 |
pde5 | 0.74 | 0.67 | 0.57 | 0.69 |
pdgfrb | 0.64 | 0.64 | 0.47 | 0.66 |
src | 0.44 | NA | 0.47 | 0.45 |
vegfr2 | 0.59 | 0.67 | 0.48 | 0.47 |
| ||||
Aver. Similarity | 0.68 | 0.73 | 0.53 | 0.60 |