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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Brain Behav Immun. 2011 Sep 21;26(2):218–227. doi: 10.1016/j.bbi.2011.09.006

Figure 1. Gamma radiation but not proton radiation reduces mouse locomotor activity.

Figure 1

Figure 1

Restraint-10 mice were exposed to 50 or 200 cGy of gamma radiation (44.5 ± 0.1 cGy/min) as indicated. Spontaneous locomotor activity and velocity of movement were measured at the time points indicated post irradiation. Results are expressed as means ± s.e.m.; n = 8. (A) Distance moved (cm): main effects of dose (P < 0.001) and time point (P < 0.001); 6 h time point: P < 0.05, sham IR v. 50 cGy (1463.8 ± 83.7 v. 968.4 ± 147.6) and sham IR v. 200 cGy (1463.8 ± 83.7 v. 950.5 ± 117.2). (B) Velocity of movement (cm/s): main effects of dose (P < 0.001) and time point (P < 0.001); 6 h time point: P < 0.05, sham IR v. 50 cGy (5.0 ± 0.3 v. 3.3 ± 0.5) and sham IR v. 200 cGy (5.0 ± 0.3 v. 3.2 ± 0.4). Bars without a common superscript are different (P < 0.05).