Skip to main content
. Author manuscript; available in PMC: 2013 Jan 17.
Published in final edited form as: Anal Chem. 2011 Dec 23;84(2):931–938. doi: 10.1021/ac202058w

Table 1.

Comparison of LOQ valuesa for some typical drugs between ET 31 chromatography paper and silica coated paper with Mini 11.

Drug Precursor
ion
Product
ion
LOQ with
Chromatography paper
(ng mL−1)
LOQ with
silica coated paper
(ng mL−1)
Therapeutic range
(ng mL−1)
lidocaine 235 86 100 20 1,000-6,000
amitriptyline 278 233 100 10 50-200
sunitinib 399 326 500 10 20-200
verapamil 455 165 100 10 50-250
citalopram 325 109 100 10 10-200
a

LOQ for each drug is defined as the lowest concentration within the set of linear responses in the sensitivity plot as shown in Figure 4, 5 a and b. Three replicates for each sample.