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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Methods. 2011 Nov 17;55(4):379–386. doi: 10.1016/j.ymeth.2011.11.003

Figure 4.

Figure 4

Demonstration of rapid plate-reading by SONICC. Top: SONICC data for a 96-well plate. Bottom: comparison of visible, conventional uv-excited fluorescence, two-photon excited UV fluorescence, and SHG for two representative wells. All images were generously provided by Formulatrix, Inc. The identity of the sample is confidential information. Acquisition times were 0.5 s per well for visible, UV, and TPE-UVF and 2.0 s per well for SHG. The field of view of each well is approximately 2 mm on each side. Crystals favorably form on the right edges of the drops. This anomaly is likely due to the dispensing robot not placing the protein and precipitate solution directly on top of one another.