Table 2.

Family-based linkage and association between COMT polymorphisms and PCOS and quantitative measures associated with PCOS.

	TDT-X2			Quantative TDT-X2
	Allele	PCOS	prolactin	BMI	uT	T
rs6269	A*:G	2.16	4.48**	0.06	0.37	0.44
rs4633	T*:C	1.23	1.19	1.51	0.1	0.35
rs4818	C*:G	2.50	4.87§	0.43	0.44	0.6
rs4680	A:G*	1.38	1.71	2.48	0.07	0.34
haplotype	ACCG	0.11	2.45	2.01	0.1	0.01
	ATCA	1.85	1.52	1.55	0.21	0.53
	GCGG	1.93	5.10¶	0.19	0.32	0.45

^*SNP allele which is over-transmitted in the TDT; major allele in parental population in bold.

nominal P-values: ** =0.034,

^§0.027,

^¶0.024.