Table 3 presents results from the mixed effects regression model examining the effects of neuroticism and acculturation on the Cortisol Awakening Response (CAR) in Mexican Americans. Results showed a significant Neuroticism × Acculturation × Time interaction (p = .0026). Mexican Americans with greater Mexican orientation and low neuroticism demonstrated a healthy, robust CAR, while the CAR was significantly attenuated in Mexican Americans with relatively greater Anglo orientation and high neuroticism.