T1DM-MCAO rats increases angiogenin expression and BMSC treatment in T1DM-MCAO rats significantly enhances angiogenin and ED1 expression. A–B, Angiogenin immunostaining and quantitative data in IBZ (A) and in the ICA (B). C, ED1 immunostaining and quantitative data in ICA. Scale bar in A–C=0.1 mm. T1DM indicates Type 1 diabetes mellitus; MCAO, middle cerebral artery occlusion; BMSC, bone marrow stromal cell; IBZ, ischemic border zone; ICA, internal carotid artery.