Figure 1.

Meta-analysis of the prognostic value of fibrosis biomarkers versus random for survival without liver-related deaths (A). Meta-analysis of the prognostic value of fibrosis biomarkers versus random for overall survival (B).

The horizontal lines indicate the 95% confidence interval for the mean difference between biomarkers and random (0.500) or between biomarkers' area under the receiver operating characteristic curves (AUROCs) and biopsy's AUROCs. The vertical lines indicate the equivalence line (0% difference). Positive differences indicate a difference in favor of the reference test (biopsy or aspartate transaminase-platelet ratio index [APRI] or FIB-4 or FibroTest or Other). When the horizontal line crosses the vertical line, there is no significant difference.

*HepaScore; †FibroMeter.