Fig. 6.

Frizzled1/2/7 regulates gene expression in endomesoderm cells. (A) Schematic representation of the endomesoderm lineage from its emergence to its segregation into endoderm and non-skeletogenic mesoderm during sea urchin embryogenesis. Adapted, with permission, from Croce and McClay (Croce and McClay, 2010). (B) Expression profile of Wnt8 and Blimp1 in control and DnFz7-injected embryos at the early blastula stage (7 hpf). (C) Expression of Gcm and FoxA, a non-skeletogenic mesoderm and an endoderm specification gene, respectively, in control and DnFz7-injected embryos at the mid-blastula stage (9 hpf). All embryos are in lateral view unless indicated ‘vv’ for vegetal view.