Table A1.

Graphical examples for the allowed binding categories.

Binding category	Description	Graphic	Binding structure class
9mer	9 Consecutive matches		9mer
8mer	8 Consecutive matches		8mer
7mer	7 Consecutive matches		7mer
6mer	6 Consecutive matches		6mer
9mer with wobble (G:U)	8 Matches + wobble + 3′ binding		6mer
8mer with wobble (G:U)	7 Matches + wobble + 3′ binding		6mer
7mer with wobble (G:U)	6 Matches + wobble + 3′ binding		6mer
8mer with miRNA bulge	8 matches + bulge + 3′ binding		6mer
8mer with mismatch	8 Matches + mismatch + 3′ binding		6mer
8mer with target bulge	8 Matches + bulge + 3′ binding		6mer
5mer	5 Matches + 3′ binding		5mer
4mer	4 Matches + 3′ binding		4mer