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. 2012 Jan 12;2012:740203. doi: 10.1155/2012/740203

Figure 3.

Figure 3

(a) Superoxide levels in femoral arteries of WT mice, EC-SOD(−/−) mice, and mice injected with CoPP. Superoxide levels were determined as described in methods. Results are mean ± SE, n = 4; *P < 0.01 versus WT, ‡ P < 0.01 versus EC-SOD(−/−); + P < 0.05 versus WT + CoPP. (b) Dose-response curves for acetylcholine-induced vascular relaxation after preconstriction with phenylephrine. Results are mean ± SE, n = 4; *P < 0.05 versus WT, ‡ P < 0.05 versus EC-SOD(−/−), + P < 0.05 versus WT + CoPP, and (c) systolic blood pressure measurements at the completion of the study (n = 4). Mice were injected with CoPP once a week as described in Methods. Blots are representative of four separate experiments. Results are expressed as mean ± SE, *P < 0.05 versus WT, ‡ P < 0.01 versus EC-SOD(−/−), + P < 0.05 versus WT + CoPP mice, and Western blot and densitometry analysis of (d) eNOS and p-eNOS.