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. 2012 Jan 15;2012:605861. doi: 10.1155/2012/605861

Figure 2.

Figure 2

Sensitivity analyses of the model parameters. Dashed lines: Scenario 1 (use of AB only); Solid lines: Scenario 2 (use of non-anti-microbial); Vertical line: baseline values; (a) Percentage of CDAD+ patients that stop AB and start non-AB (baseline = 50%, σ = 0.5); (b) Number of colonized patients admitted per day in the ratio λ C− off⁡/λ C− on⁡ = 2/3 (baseline λ C− off⁡ = 0.33, λ C− on⁡ = 0.5); (c) Length of stay of colonized patients in weeks (baseline = 4 weeks, = γ C− off⁡/γ C− on⁡= 1/28); (d) Hand-washing compliance percentage (baseline = 60%, η = 0.6); (e) Percentage of uncolonized and colonized patients on AB (held equal) that become CDAD+ (baseline = 15%, ω U− on⁡ = ω C− on⁡ = −log (0.9893)); (f) Time to symptoms resolution (TSR) of colonized CDAD+ patients on AB in days (baseline = 3.7 days, δ C+ on⁡ = −log (0.73)); AB = antibiotic; CDAD = clostridium difficile-associated disease; non-AB = nonantibiotic; λ C− off⁡ = CDAD−, colonized, off antibiotic: admission rate; γ C− on⁡ = CDAD−, colonized, on antibiotic: average length of stay; ω U− on⁡ = CDAD−, uncolonized, on antibiotic: transit to CDAD+; ω C− on⁡ = CDAD−, colonized, on antibiotic: transit to CDAD+; γ C− off⁡ = CDAD−, colonized, off antibiotic: average length of stay; λ C− on⁡ = CDAD−, colonized, on antibiotic: admission rate.