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. 2011 Nov 29;119(3):838–846. doi: 10.1182/blood-2011-04-346098

Figure 3.

Figure 3

CFU-MK production is heightened with Cib1 deletion. (A) Representative histograms of DNA content of CD41+ BM cells derived from WT and Cib1−/− mice. (B) Quantification of the ploidy distribution of WT and Cib1−/− BM megakaryocytes expressed as a percentage of total megakaryocytes (n = 6). (C) Representative light-microscopic images of CFU-MK stained with acetylcholinesterase after 7 days in culture. Arrows indicate CFU-MK colonies. (D) Quantification of the number of CFU-MK in each well after 12 days of incubation. Colonies were composed of at least 3 cells. *P < .05 vs WT (n = 4).