Table 4.
Preoperative diagnosis of breast cancer | N for CSM | N for standard PM | Number of CSM | Definition of negative margin | Reduction in reexcision | P value | |
---|---|---|---|---|---|---|---|
Cao et al. [6] | Unknown | 126 | N/A | 4–6 | 2 mm | 61/103a | |
Hewes et al. [7] | Yes | 957 | N/A | 4 | 1 mm | 107/196b | |
Huston et al. [8] | Yes | 45 | 49 | 4–6 | 2 mm | 21%c | |
Jacobson et al. [9] | Unknown | 125 | N/A | 4–6 | 2 mm | 61/83d | |
Marudanayagam et al. [10] | Yes | 394 | 392 | 4 | Absence of tumor at resected margin | 6.92%e | <0.01 |
Rizzo et al. [11] | Yes | 121 | 199 | 4–5 | 1 mm | 27.90%f | <0.05 |
Tengher-Barna et al. [12] | Yes | 107 | N/A | 4 | 3 mm | 24/47 g |
CSM: cavity shave margin; PM: partial mastectomy.
a,b,d,gThe overall final shave margin status was histologically negative in said amount of patients with histologically positive lumpectomy margins; therefore, areexcision was avoided in these patients.
cReexcision rate in PM group 38.7% versus 17.7% in CSM group.
eReexcision rate in PM group 12.5% versus 5.58% in CSM group.
fReexcision rate in PM group 85.1% versus 57.2% in CSM group.