Table 2.
The chief complaints, clinical effects, and anatomical locations of the stimulated contacts in 11 patients treated with deep brain stimulation.
| Case no. | UPDRS | Localization of stimulated contact | AC-PC (mm) | RN (mm) | Akinesia | Tremor | Gait disturbance | On-Off (%/day) | Dyskinesia (%/day) | Levodopa equivalent (mg/day) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Right | Left | Right | Left | |||||||||||||||||
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | |||||
| 1 | 19 | 10 | ZI | ZI | 22 | 4.8 | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 50 | 20 | 70 | 30 | 565 | 468 |
| 2 | 26 | 9 | FH | FH | 22 | 6.0 | 5 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 20 | 20 | 70 | 30 | 347 | 280 |
| 3 | 28 | 16 | ZI | FH | 21 | 6.0 | 5 | 2 | 1 | 0 | 2 | 0 | 4 | 3 | 40 | 0 | 0 | 0 | 533 | 418 |
| 4 | 31 | 15 | ZI | ZI | 21 | 6.0 | 8 | 1 | 0 | 0 | 5 | 0 | 5 | 4 | 60 | 0 | 50 | 0 | 628 | 400 |
| 5 | 19 | 4 | ZI | STN | 20 | 6.0 | 2 | 1 | 2 | 0 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 342 | 271 |
| 6 | 28 | 12 | STN | STN | 23 | 4.0 | 3 | 1 | 3 | 1 | 3 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 396 | 253 |
| 7 | 44 | 25 | ZI | STN | 24 | 6.0 | 10 | 7 | 3 | 0 | 3 | 1 | 5 | 3 | 0 | 0 | 0 | 0 | 557 | 590 |
| 8 | 73 | 60 | ZI | FH | 25 | 5.4 | 10 | 7 | 2 | 0 | 2 | 0 | 10 | 10 | 70 | 50 | 50 | 20 | 503 | 503 |
| 9 | 24 | 7 | STN | STN | 21 | 5.6 | 1 | 0 | 3 | 0 | 2 | 0 | 4 | 3 | 30 | 0 | 50 | 20 | 570 | 500 |
| 10 | 44 | 16 | FH | FH | 21 | 6.0 | 6 | 2 | 3 | 0 | 3 | 0 | 4 | 3 | 0 | 0 | 70 | 20 | 285 | 285 |
| 11 | 13 | 4 | ZI | No placement | 24 | 5.0 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 440 | 307 |
| Mean | 31.7 | 16.5 | 22.2 | 5.5 | 5 | 1.9 | 1.5 | 0.1 | 2.6 | 0.1 | 4.2 | 2.9 | 24.5 | 8.2 | 32.7 | 10.9 | 470 | 388.6 | ||
| ± S.D. | 16.7 | 15.6 | 1.6 | 0.7 | 3.3 | 2.6 | 1.4 | 0.3 | 1.7 | 0.3 | 2.4 | 2.7 | 27.0 | 16.0 | 32.3 | 13.0 | 113.5 | 116.1 | ||
Akinesia: UPDRS II items 9, 10, 11, 12, 13, 14, 15, on-off and percentage of daily time spent in off states, tremor: UPDRS III items 20 and 21, gait disturbance: UPDRS III items 27, 28, 29, and 30, dyskinesia: the percentage of daily time spent in dyskinesia, rigidity: UPDRS III item 22 on the side contralateral to DBS stimulation.
AC-PC: distance of anterior commissure-posterior commissure, RN: lateral distance from the midline of red nucleus, ZI: zona incerta, STN: subthalamic nucleus, FH: field of forel H, and mean ± S.D.: mean ± standard deviation, pre: before surgery, post: after surgery.