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Normalized luciferase activity of the putative IRAK3 promoter constructs carrying −1464A and −1464G alleles. Control sample is represented by a promoter-less construct, whereas −1464A and −1464G stand for the A and G allele constructs for rs1732887, respectively. Both show higher luciferase activity than the control sample (P ≤ 0.01). The data represent mean values ± SEMs from four independent experiments, normalized to the −1464A construct.
