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. 2010 Sep 21;2011:963159. doi: 10.1155/2011/963159

Table 1.

Summery of the literature on nedaplatin-based concurrent chemoradiotherapy.

Author (Reference) Year Study type Setting Stage Results
J. Kodama [19] 2008 Phase I Postoperative RT Ib-IIb Weekly 35 mg/m2 of nedaplatin was recommended.
Y. Kobayashi [21] 2009 Retro Postoperative RT Ib2-IIb Biweekly 70 mg/m2 of nedaplatin was employed. CCRT was better than RT alone, but the improvement was not significant.
S. Mabuchi [20] 2009 Retro Postoperative RT IA2-IIb Weekly 40 mg/m2 of nedaplatin was employed.
CCRT was significantly better than RT alone.

Y. Onishi [14] 2002 Phase I Definitive RT III-IVa Weekly 30 mg/m2 of nedaplatin was recommended.
K. Yoshinaga [15] 2007 Phase I Definitive RT Ib2-IIIb Weekly 35 mg/m2 of nedaplatin was recommended.
Y. Yokoyama [16] 2008 Phase II Definitive RT Ib2-IVa Weekly 30 mg/m2 of nedaplatin was employed.
Y. Niibe [17] 2008 Phase II Definitive RT IIIa-IVa Weekly 30 mg/m2 of nedaplatin was employed.
S. Mabuchi [18] 2010 Retro Definitive RT IIIb Weekly 35mg/m2 of nedaplatin was employed.
CCRT was significantly better than RT alone.

CCRT: concurrent chemoradiotherapy, Retro: retrospective cohort study, RT: radiotherapy.