Table 4.
Candidates for PC surveillance (with >10-fold increased risk of PC) |
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Anyone with ≥3 first-degree relatives with PC |
Individuals with ≥3 first-, second-, or third-degree relatives with PC, at least one of whom is a first-degree relative |
Anyone with FAMMM, PJS, or HP |
Any member of a PJS family |
Carriers of mutations of BRCA1, BRCA2, or an MMR gene and with at least one first- or second-degree relative with PC |
A person with 2 relatives in the same lineage (directly connected) with PC, at least one of whom is a first-degree relative of the candidate |
Some people with two first-degree relatives with PC and favorable expert opinion |
Modified from [50].