Table 2.
Antiplasmodial activity and cytotoxicity of the tested products.
| Scientific name (Family) | Part used (Code) | IC50 on 3D7 (μg/mL) | IC50 on DD2 (μg/mL) | CC50 on LLC/MK2 (μg/mL) | SI on 3D7 (SI on DD2) |
|---|---|---|---|---|---|
| Cuviera longiflora | Leaves (CLL) | 20.24 ± 4.95 | 13.91 ± 0.65 | 250 | 12.35 (17.91) |
| Dacryodes edulis (Burseraceae) | Leaves (DEL) | 6.45 ± 0.88 | 8.62 ± 1.44 | >1000 | ND |
| Eucalyptus globulus | Leaves (EGL) | 16.80 ± 8.35 | 26.45 ± 3.32 | 208.33 | 12.40 (7.88) |
| Kotschya speciosa | Whole plant (KS) | 48.29 ± 4.46 | 108.89 ± 17.21 | >1000 | ND |
| Aerial part (KSH) | 22.61 ± 10.34 | ND | 625 | 27.64 | |
| Aerial part (KSR) | 64.30 ± 12.76 | 59.30 ± 8.32 | >1000 | ND | |
| Coula edulis | Stem bark (CE) | 13.80 ± 3.25 | 5.79 ± 1.33 | 178.57 | 12.94 (30.84) |
| Vernonia amygdalina | Leaves (VAL) | 8.72 ± 2.11 | 11.27 ± 2.06 | >1000 | ND |
| Root bark (VAR) | 9.01 ± 1.11 | ND | >1000 | ND | |
| Vismia guinensis | Stem bark (VGE) | 43.42 ± 2.76 | 4.735 ± 3.54 | >1000 | ND |
| Stem bark (VGS) | 65.29 ± 7.58 | 62.5 ± 12.45 | >1000 | ND | |
| Chloroquine | 0.10 | 0.95 ± 0.01 | — | — | |
IC50: inhibition 50%, CC50: cytotoxic concentration 50%, each value represents the average and standard deviation obtained from 6 different measurements; ND: not determined.