Figure 3.

Adjusted all-cause mortality risk by dialysate sodium (DNa) and predialysis serum sodium (SNa). Cox model using a single reference point (predialysis SNa category: 138–139 mEq/L; DNa category: 140 mEq/L), stratified by phase and region and adjusted for age, race, sex, vintage, body mass index, diabetes, 13 other comorbid conditions, residual renal function, vascular access, serum albumin, hemoglobin, serum creatinine, ferritin, white blood cell count, and facility clustering. Test for SNa × DNa interaction was not significant (P=0.92). Overall tests for trend were significant for SNa (P<0.0001) but not for DNa (P=0.29). Data are shown with 95% confidence intervals. HR, hazard ratio.