Figure 4.

Adjusted hospitalization risk by dialysate sodium and predialysis serum sodium. *Hospitalizations of all-cause but non–vascular access-related conditions were analyzed. Cox model using a single reference point (predialysis serum sodium [SNa] category: 138–139 mEq/L; dialysate sodium [DNa] category: 140 mEq/L), stratified by phase and region and adjusted for age, race, sex, vintage, body mass index, diabetes, 13 other comorbid conditions, residual renal function, vascular access, serum albumin, hemoglobin, serum creatinine, ferritin, white blood cell count, and facility clustering. Test for SNa × DNa interaction was not significant (P=0.61). Overall tests for trend were significant for both SNa (P<0.0001) and DNa (P=0.04). Data are shown with 95% confidence intervals. HR, hazard ratios.